HMGB1 and colorectal carcinoma: Finally, HMGB1 overexpression has been shown to correlate with advanced clinical stage or decreased disease-free and/or overall survival amongst 164 patients with bladder carcinoma (175), 166 individuals with nasopharyngeal carcinoma (176), 192 CRC patients (177), 208 and 161 individuals with HCC (178, 179), 103 subjets with head and neck squamous cell carcinoma (180), as well as 85 patients with prostate cancer (181).