IFNB1 and infection: Total RNA samples prepared from cells infected with any of the IFN-β-inducing viruses, SeV-CNT, 4C(-), and NDV, were able to induce the granules as well as IFN-β in HeLa cells despite no formation of the granules by the CNT infection, whereas those from cells infected with the IFN-β-non-inducing SeV-Z-WT or treated with arsenite were not (Figure 4A).