The activation of PKR has been reported to induce the formation of SG-like structures during infections by some RNA viruses, such as IAV and measles virus (MeV; Mok et al., 2012; Onomoto et al., 2012; Okonski and Samuel, 2013), and this also appears to be the case for the SeV C recombinants. This evidence concerns the gene EIF2AK2 and infection.