Further in vitro and in vivo studies demonstrated that these responses were predominantly Th-1 mediated (Miyata et al., 1996; Koga et al., 2001; Brasch, 2009; Santiago et al., 2014), although recent evidence in experimental models of dermatophytosis also pointed to Th-17 responses (Cambier et al., 2014). The gene discussed is NELFCD; the disease is dermatophytosis.