Many Kampo products and active components have been reported to moderate an array of processes in cancer cell growth, invasion and metastasis by modulating a broad range of molecular targets, including: cyclooxygenase-2 (COX-2), NF-kappaB and NF erythroid 2-related factor 2-mediated antioxidant signaling pathways (Wang et al., 2010). Here, PTGS2 is linked to cancer.