LMPs extracted from the joints of patients with RA induce the release of IL-6, CCL1, CCL2, and CCL5 by FLSs from the same individuals [95], and MPs obtained from Jurkat cells and U937 human promocytes induce the production of angiogenic chemokines such as CXCL1, CXCL2, CXCL3, CXCL5, and CXCL6 by FLSs from RA patients. This evidence concerns the gene CCL2 and rheumatoid arthritis.