Subsequently, this has also been shown in another dataset of 580 triple negative breast cancer (TNBC) and HER2-positive breast cancers (59.9 % in LPBC vs 33.8 % in non-LPBC) [41] as well as in a meta-analysis of 996 patients where an immune gene module indicative of a Th1 response was prognostic of pCR in all cancer subtypes [61]. This evidence concerns the gene ERBB2 and breast carcinoma.