Control mice included non-depleted, non-engrafted mice with MRgHIFU heated tumor (n = 3), depleted, non-engrafted mice with MRgHIFU heated tumor (n = 3) and depleted hsp/lucF engrafted mice with tumor placed in the MRgHIFU device but without applying ultrasound (n = 3). This evidence concerns the gene HSP90B2P and neoplasm.