POT1 and acute myeloid leukemia: Genetic alterations resulting in enhanced telomerase activity have recently been implicated in a variety of bone marrow failure syndromes such as acute myeloid leukemia [7, 17–18] inducing an expansion of undifferentiated myeloid hematopoietic stem cell progenitors, but so far no somatic mutations in either TERT or POT1 genes have been described in acute myeloid leukemia (AML).