Wu et al. investigated the cell functions by introducing TAp63α and ΔNp63α into Saos2 cells using adenovirus expression vectors and subsequently detecting the gene profiles using DNA microarrays, and they have found that p63 can regulate a wide range of various cellular functions, such as cell cycle control, stress, and signal transduction, which are critical events in cancer and development [32]. Here, TP63 is linked to cancer.