More thorough hormonal assessments should include testosterone which has been found associated with unipolar depression during the MT (Bromberger et al. 2010), inhibin B, an early indicator of ovarian aging, and potentially sex hormone-binding globulin as well as dehydroepiandrosterone which have both been assessed in association with unipolar depression during the menopausal transition (Bromberger et al. 2010). The gene discussed is SHBG; the disease is major depressive disorder.