YAP1 and cancer: Here, we comprehensively mapped YAP1 chromatin binding genome-wide, independent of gene location, using ChIP-seq in two human cancer cell lines from different lineages with elevated YAP1 activity (SF268 and NCI-H2052) as well as in non-transformed cells (IMR90) enabling an unbiased identification of YAP1 binding sites and their dependence on cellular context.