PIK3C2A and cystic kidney disease: In our initial studies, we characterized the renal cystic disease severity of 10-d old Cys1cpk/cpk mice generated from the B6.CAST.4PM-Cys1cpk/+cross and compared it to the renal phenotypes of Cys1cpk/cpk mice generated from the B6.4PM-Cys1cpk/+cross.