Notably, 92 AR interacting proteins are also lysine acetylated and play an important role in chromatin remodeling (Figure 3 and Supplementary Table 3), and are involved in various biological processes, as well as and pathways that facilitates prostate cancer development (Supplementary Table 4), suggesting a critical role for post translational modifications in AR-mediated processes. This evidence concerns the gene AR and prostate carcinoma.