When considering glioma patients as one group irrespective of histological grade, the increased expression of 15 genes (CENPA, DLG7, PBK, FILIP1L, CDC6, MCC, KIF15, MPP6, KIF18A, EZH2, DEPDC1, HMMR, P2RY5, FAM118A, and FNDC3B) correlated with the least favorable survival (Supplementary Figure S6A). The gene discussed is SIRAL2; the disease is central nervous system cancer.