F2 and atherosclerosis: These pathways are involved in lipid metabolism (LXR/RXR activation, oleate biosynthesis II), cholesterol biosynthesis (cholesterol biosynthesis I/II/III, superpathway of cholesterol biosynthesis, zymosterol biosyntheis), amino acid synthesis (serine biosynthesis, superpathway of serine and glycine biosynthesis), coagulation (intrinsic/extrinsic prothrombin activation pathway, coagulation system), and endocrine functions (estrogen biosynthesis, atherosclerosis signaling, axonal guidance signaling, retinoate biosynthesis I).