In the present study, we aimed to determine (i) the effect of acupuncture on dyspeptic symptoms, quality of life, and mental status in patients with FD; (ii) the effect difference between classic acupuncture based on TCM principles and acupuncture on nonacupoints; and (iii) effects of classic acupuncture on serum gastrin concentration and frequency and propagation velocity of gastric slow waves. The gene discussed is GAST; the disease is Fabry disease.