In recent years, several readily measurable peripheral blood markers such as the neutrophil to lymphocyte ratio (NLR) [5–10], the Glasgow Prognostic score (consisting in a combination of C-reactive protein and albumin level) [11–13], the platelet to lymphocyte ratio [14, 15] or the Prognostic index (consisting in white blood cell count and C-reactive protein) [16], were associated with cancer outcomes in large cohort studies. The gene discussed is CRP; the disease is cancer.