BTK and acute myeloid leukemia: Protein Kinase B (AKT), phosphatidylinositol 3-kinase isoform p110delta (P13-K), Signal Transducer and Activator of transcription 5 (STAT5), Mitogen-Activated Protein Kinase (MAPK) and Bruton’s tyrosine Kinase (BTK), have all been shown to be part of pathways that regulate AML survival8, 9, 10, 11.