CRP and coronary artery disorder: An analysis using genome-wide genetic scores for various risk factors gave false negative and false positive results; it suggested that CRP was a causal risk factor for coronary heart disease risk (P = 0.028), but BMI was not (P = 0.37) and suggested an inverse effect of low-density lipoprotein cholesterol on hypertension (P = 0.011) and on type 1 diabetes risk (P = 0.018) [45].