TMEM163 and type 2 diabetes mellitus: Noteworthy, a T2D associated SNP, rs6723108 (TMEM163), has reached near fixed high risk allele frequency (0.98 in our sample compared to 0.51 in the Caucasian sample of 1000 G project) and has a substantial population difference with the Caucasian (FST as high as 0.61).