To our knowledge, the T2D association of rs7578326 (IRS1), rs1531343 (HMGA2), rs8042680 (PRC1), rs1387153 (MTNR1B), rs7578597 (THADA) [25], rs243021 (BCL11A) [26], and rs1333051 (CDKN2) [27] was replicated in an East Asian sample for the first time. The gene discussed is IRS1; the disease is type 2 diabetes mellitus.