We tested whether there were significant associations between the elevations of each antibody isotype (IgG, IgA, and IgM) of the brain proteins (MBP, MOG, S100B, and human aquaporin) with the corresponding antibody isotype of the food proteins (soy, corn, tomato, and spinach aquaporins) in RRMS patients. The gene discussed is MOG; the disease is relapsing-remitting multiple sclerosis.