In the univariate analysis, the following variables were associated with vitamin D deficiency: higher levels of total bilirubin, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and creatinine; lower levels of calcium and transferrin; use of vitamin D supplementation, NSAID and corticosteroids and the presence of PSC as shown in Table 1. The gene discussed is TF; the disease is vitamin D deficiency.