Although quiescent normal HSCs reportedly produce adenosine 5′-triphosphate through anaerobic glycolysis19, 20, we observed no differences in levels of glucose, fructose 1,6-bisphosphate or pyruvate between normal KLS+ cells and CML-KLS+ cells (Fig. 1a; Supplementary Data 1). The gene discussed is RPS6KB2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.