NCOA1 and breast cancer: Semi-quantitative analysis revealed that MVD is reduced 70% and 60% in Ncoa1 knockout (Ncoa1−/−) mammary tumors versus Ncoa1 wild type (Ncoa1+/+) mammary tumors at week 8 and week 13 after the detection of palpable tumors in Tg(MMTV-PyMT) mice (Figure 1a and 1b).