EGFR and lung carcinoma: As discussed above, miR-7 is a well-established regulator of EGFR, however it was also shown that miR-7 might be regulated by EGFR signaling: EGFR activation in lung cancer cells can stimulate miR-7 expression in an ERK-dependent manner, suggesting that EGFR induces miR-7 expression via the RAS-ERK pathway [68].