MAP1LC3A and osteosarcoma: The involvement of autophagy and LC3 in DMV formation was further clarified when LC3 was shown to colocalize with MHV proteins nsp2/nsp3, dsRNA, and ER-associated degradation (ERAD) vesicle markers ER degradation-enhancing alpha-mannosidase-like 1 (EDEM1), Osteosarcoma amplified 9 (OS-9) in embryonic fibroblasts [113].