Hainanerectamines B (153) and C (800) display moderate inhibitory effects on the serine/threonine kinase Aurora A (IC50 24.5 and 18.6 μg/mL), which is involved in cell division regulation, but none of the compounds had cytotoxic effects on the tumor cell lines A549 and HT-29 [98]. Here, MARK2 is linked to neoplasm.