Cleaved caspase 1 (p20) (P < 0.05), cleaved caspase 3 (p17, 19) (P < 0.01), cleaved caspase 8 (p18, 43) (P < 0.05), cleaved caspase 9 (p37, 39) (P < 0.05), and TNF-stimulated gene 6 protein (TSG6) (P < 0.05) could be significantly identified in Sal-YB1-treated tumor mass by Western blotting (Fig. 6b–g). This evidence concerns the gene CASP3 and neoplasm.