Moreover, in BALB/c mice, the level of infection measured by adult worm burdens at day 28 positively correlated with the number of Helios+ tTregs (Figure 1f) but not with numbers of Helios− pTregs (data not shown), and there was an even stronger positive correlation with the number of CD103+Helios+ tTregs (Figure 1g). The gene discussed is ITGAE; the disease is infection.