CD4 and infection: These data suggest that tTregs respond rapidly and are able to predominate at gastrointestinal mucosal surfaces following H. polygyrus infection.36 In addition, we profiled the distribution of TCR Vβ expression within Tregs in naive and infected mice; among almost all Vβ types, there was an increase in the proportions of CD4+ T cells expressing Foxp3 and CD103 following infection (Figure 2c).