CRP and Increased total leukocyte count: Table 1 shows that ProADM with a 0.16 nmol/L cut-off was very efficient to rule out bacteremia (sensitivity and NPV = 100 %, LR- 0.14 [0.01–2.00]), as accurate as CRP (>100 mg/L) and better than band neutrophils (>1.5 G/L) or leukocytosis (>15 G/L).