Therefore, in order to address this issue, we measured relative quantities of seven selected molecular markers associated with rejection or tolerance (CD247, GZMB, PRF1, MAN1A1, TLR5, FOXP3 and TCAIM) and numbers of lymphocyte subpopulations (CD3+, CD4+, CD8+, NK, CD4+FOXP3+) in the peripheral blood of kidney transplant recipients treated with rATG, basiliximab or no-induction. The gene discussed is PRF1; the disease is medical procedure.