A total of 550 adverse events were observed in this trial that included one event of severe anemia in the multivitamin arm, and one in the placebo arm (p = 0 · 995), 345 events of nausea (153 in the multivitamin and 192 in the placebo arm; p = 0 · 088), 200 cases of vomiting (84 in the multivitamin, and 116 in the placebo arm; p = 0 · 058), and one event of high ALT (>200 IU/I) in the multivitamin arm compared to none in the placebo arm; p = 0 · 496, (Table 3). Here, GPT is linked to anemia (phenotype).