SERPINE1 and acute respiratory distress syndrome: 66.6 % of these genes, were associated previously with lung injury and include the well known ARDS genes such as IL1R2 (P = 4.42 × 10−19), IL1β (P = 3.38 × 10−17), PAI1 (P = 9.59 × 10−14), IL6 (P = 3.57 × 10−12), SOCS3 (P = 1.05 × 10−10), and THBS1 (P = 2.01 × 10−9).