RBPJ and infection: Fig 2A showed there was no detectable RBPJK expression in RBPJK shRNA lentiviral infected MSCs by Western blotting analysis when compared to shCo/MSCs at day 3 after infection. Although we saw a mild detectable expression of RBPJK at day 14 in lentiviral infected MSCs, and the level is significant lower than that in shCo/MSCs. These fold changes in protein level of RBPJK in Western blots were further quantified by measuring band intensity (Fig 2B).