A meta-analysis of 56 studies examining subjects of European descent demonstrated the presence of better cardiovascular markers (including low levels of serum non-HDL-C, body mass index [BMI], and blood pressure) and lower risks of coronary heart disease and ischemic stroke among drinkers with the ADH1B*2 allele, compared with drinkers with the ADH1B*1/*1 genotype [20]. The gene discussed is ADH1B; the disease is ischemic stroke.