Further, we nominally replicated (P<0.05), in the same direction, seven of the eleven previously identified Chinese PCOS SNPs (Table 3), including gonadotropin receptor genes LH/CGR and FSHR, as well as THADA, DENND1A, YAP1, and RAB5B/SUOX14, 15, exceeding the number of associations we would expect to replicate by chance alone. The gene discussed is LGR6; the disease is polycystic ovary syndrome.