MMP2 and neoplasm: Zymogels analysis, and quantification of MMP activities showed that co-cultures of LS174T with either NHF (Figure 2A, lane c and Figure 2B–2C) or MEF (Figure 2A, lane e and Figure 2D–2E) did not significantly produce more MMP2 and MMP9 than tumour cells or fibroblasts cultured alone (Figure 2A, lanes a, i, j and Figure 2B–2E).