Additionally, these markers are usually analysed separately and a combined analysis may provide a better approximation with respect to early cancer detection, as it has shown in the case when combining scores of CRP with IL-8 [108] or haptoglobin with serum amyloid A (SAA) [109] in predicting lung cancer risk, and the ratio of reactive oxygen metabolites and CRP for colorectal cancer [110]. The gene discussed is CRP; the disease is lung cancer.