SGCG and schistosomiasis: Despite the fact that protective immunity to S. mansoni and S. haematobium infection in humans is documented to be dependent on type 2 immune responses (2, 3, 5, and references therein), formulations of schistosomiasis vaccines destined for use in humans still aim to induce predominant type 1-related cytokines and antibodies, clearly indicating we have not yet reached a consensus regarding the type of immune responses an anti-schistosomiasis vaccine should elicit.