CD1A and tuberculosis: Despite a low affinity interaction (100 μM) between a DDM-specific TCR and CD1a–DDM soluble molecules (23), DDM–CD1a dextramers have been successfully used to stain DDM-specific T cells ex vivo in patients with active tuberculosis or positive tuberculin test, and could be a useful tool to determine the phenotype and function of these cells at a population level (23).