NF-κB is activated in dopaminergic neurons in the SNpc of PD patients (Hunot et al., 1997), in peripheral immune cells in patients with HD (Trager et al., 2014) and, in hippocampal and entorhinal cortex neurons of AD patients, but not in glial cells (Terai et al., 1996; Kaltschmidt et al., 1997; Ferrer et al., 1998). The gene discussed is NFKB1; the disease is Huntington disease.