Analysis of the serous ovarian cancer microarray dataset from The Cancer Genome Atlas project shows that SRSF3, BRCA1, RAD51, XRCC2 and BLM are upregulated in tumors compared to normal ovaries, as shown in Additional file 3: Figure S7, supporting the notion that tumor cells need enhanced HRR activity. The gene discussed is SRSF3; the disease is ovarian serous adenocarcinoma.