CD4 and tuberculosis: Multivariable Cox regression analysis identified a positive IGRA (adjusted hazard ratio [HR] 5.04, 95% CI 1.76–14.46, p = 0.003) and an HIV viral load ≥ 100,000 copies/mL (adjusted HR 8.75, 95% CI 1.22–62.56, p = 0.03) (Table 3) as independent risk factors for incident active TB, after adjusting for age, CD4 cell count and HIV viral load.