IL4 and amyotrophic lateral sclerosis: IL-4 and eotaxin/CCL11 levels were higher in patients with ALS with lower ΔALSFRS-R (r = −0.454, p = 0.026 and r = −0.579, p = 0.003, respectively), indicating that those cytokines are found at higher levels in patients with slower disease progression (figure 2).