Pathology reports may include, at least, the pathological diagnosis of GIST, tumor origin, presence of preoperative or intraoperative rupture, histological type, maximal size (cm), mitotic index (area of 5 mm2), surgical margin, immunohistochemical findings (KIT, DOG1, CD34, desmin, S100, Ki67), presence of pathological necrosis, risk stratification, and KIT and PDGFRA mutations. The gene discussed is DES; the disease is neoplasm.