In the vast majority of samples, FAK/p-GSK3α/βY279/Y216/β-catenin (19 of 26 samples) and PYK2/p-GSK3α/βY279/Y216/β-catenin (18 out of 26 samples) were regulated in the same way, supporting that they are related events in the development of colonic cancer (Figure 6C). The gene discussed is GSK3A; the disease is malignant colon neoplasm.