Such protective effects have been noted in clinical and prospective studies (3), and it has been learned in the past few years that FA profiles with low proportions of LA (18:2-6) predict myocardial infarction (4,55), stroke (56), left ventricular hypertrophy (57), insulin sensitivity (14), glucose intolerance (61) and metabolic syndrome (58,60). This evidence concerns the gene INS and left ventricular hypertrophy.