HGF and lung cancer: Using a similar approach, Zhou et al. found that an ectopic expression of miR-34a could inhibit cell growth and induce apoptosis in hepatocyte growth factor- (HGF-) induced gefitinib-resistant HCC827GR and PC-9GR lung cancer cells and in HGF-induced gefitinib resistant mouse xenograft model, partly by targeting MET [51].