An aetiopathological link between SDHx mutations and pituitary tumours is strongly suggested by case reports of pituitary tumours that demonstrate loss of SDHB immunostaining, occurring in patients who carry germline mutations in SDHA (Dwight et al. 2013b, Papathomas et al. 2013), SDHB (Xekouki et al. 2015), SDHC (Lopez-Jimenez et al. 2008) and SDHD (Xekouki et al. 2012). Here, SDHC is linked to pituitary tumor.