In addition to SLC34A1 p.Tyr489Cys, we found a rare missense variant in TRPV5 (NP_062815.2:p.Leu530Arg (MAF=0.13 %) associating significantly with recurrent kidney stones (OR=3.62, P=4.1 × 10−5<0.05/220=2.3 × 10−4) (Table 3). Here, TRPV5 is linked to nephrolithiasis.